Some people feel dexamethasone, a steroid, is a wonder drug. The controlled, double-blind studies did not show it to be so wonderful. It does prevent AMS but does not aid acclimatization, as Acetazolamide does. Acetazolamide both prevents and treats AMS. Steroids can cause euphoria or depression. In addition, if your pills were to get lost or avalanched off, you would be in dire straits. The side effect profile does not warrant even thinking of using this drug routinely. Competitive athletes are disqualified for using this pharmacologic agent; should climbers be any different ?